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geNorm is the most popular algorithm to find stable reference genes

 

The underlying principles and formulas are described in Biogazelle's co-founder's seminal paper from 2002: Vandesompele et al., Genome Biology, 2002, 'Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes'. The full article can be read at here.

The Microsoft Excel geNorm version from 2002 has been downloaded more than 15,000 times worldwide. Since 2010, a much improved geNorm module is integrated in the qbasePLUS software (both basic and premium license) for real-time PCR data analysis in Windows, Mac and Linux.

 

Did you know that

  • the geNorm article is n° 7 in ranking of all time most-viewed articles published by BioMed Central
  • more than 15,000 users downloaded geNorm
  • geNorm is used in more than 126 countries
  • geNorm is cited over 3,000 times according to Google Scholar